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Common factors regulating patterning of the nervous and vascular systems
(Annual Reviews, 2010)
The vascular and the nervous systems of vertebrates share many features with similar and often overlapping anatomy. The parallels between these two systems extend to the molecular level, where recent work has identified ...
Regulation of axonal development by the nuclear protein hindsight (pebbled) in the Drosophila visual system
(Academic Press Inc., 2010)
The molecules and networks involved in the process of acquisition and maintenance of the form of a mature neuron are not completely known. Using a misexpression screen we identified the gene hindsight as a gene involved ...
Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in axon guidance in Drosophila
(John Wiley and Sons Inc., 2015)
© 2015 Wiley Periodicals, Inc.During axon targeting, a stereotyped pattern of connectivity is achieved by the integration of intrinsic genetic programs and the response to extrinsic long and short-range directional cues. ...
Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance
(Company of Biologists, 2020-04)
Endocannabinoids (eCB) modulate growth cone dynamics and axonal pathfinding through the stimulation of cannabinoid type-1 receptors (CB1R), the function of which depends on their delivery and precise presentation at the ...
Slit neuronal secretion coordinates optic lobe morphogenesis in Drosophila
(Elsevier, 2020)
The complexity of the nervous system requires the coordination of multiple cellular processes during development. Among them, we find boundary formation, axon guidance, cell migration and cell segregation. Understanding ...
New insights on epigenetic mechanisms supporting axonal development: Histone marks and miRNAs
(Wiley Blackwell Publishing, Inc, 2020-12)
Mechanisms supporting axon growth and the establishment of neuronal polarity have remained largely disconnected from their genetic and epigenetic fundamentals. Recently, post-transcriptional modifications of histones ...
Estudio del tráfico local de la proteína L1CAM en axones de neuronas del sistema nervioso central
(Universidad de Chile, 2020)
Las neuronas son células altamente compartimentalizadas y polarizadas en 2
dominios funcional y estructuralmente distintos: el somato-dendrítico y el axonal. La
mantención y diferenciación de ambos dominios es fundamental ...
Inhibitory effect of semaphorin-3A, a known axon guidance molecule, in the human thymocyte migration induced by CXCL12
(Society for Leukocyte Biology, 2017)